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Counting human chromosomes before 1960: preconceptions, …
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(PDF) How to count chromosomes in a cell: An overview of
ABSTRACT. In the biomedical world was surprised to hear a report that human cells each contained forty six chromosomes, rather than the forty eight count that had been Missing: makro Human cytogenetics was born in with the fundamental, but empowering, discovery that normal human cells contain 46 chromosomes. Since then, this field and our Missing: makro Or more precisely: these cells are able to count their own X-chromosomes. This is possible by physical interaction between all X-chromosomes present in a nucleus at a certain phase of the cell cycle; this phenomenon was given the romantic sounding name ‘chromosome-kissing’ (Fig. 1A). The gene which is involved in this chromosome