M-NFS cell proliferation induced by human M-CSF. Recombinant human M-CSF induces the proliferation of mouse M-NFS60 cell line in a dose dependent manner. Missing: illustrator Based on this, the key factor by which recombinant GM-CSF enhances the bactericidal-related functions of PMNs seems to be clear, and it is most likely IL-1β. Recombinant GM-CSF increased the transcription and expression of the IL1B gene in PMNs through the GM-CSF receptor on the surface of PMNs and generated more IL1B Animal Free and Xeno Free. Tag Free. Source: Human cells derived. Structure: Glycosylated homodimer. Activity: N/A. Purity: >95% by SDS-PAGE. Endotoxin Level: Missing: illustrator High levels of M-CSF have been associated with different pathologies such as pulmonary fibrosis and atherosclerosis. M-CSF binds to its receptor M-CSFR, and this receptor is shared by a second ligand, IL Human M-CSF and IL exhibit cross-species specificity – both bind to human and mouse M-CSF receptors. Product Details Background: M-CSF. M-CSF, also known as CSF-1, is a four-alpha -helical-bundle cytokine that is the primary regulator of macrophage survival, proliferation and differentiation (1 - 3). M-CSF is also essential for the survival and proliferation of osteoclast progenitors (1, 4). M-CSF also primes and enhances macrophage killing of tumor cells and Product Specific Information. Recombinant Human M-CSF is a kDa homodimeric protein consisting of two amino acid polypeptide subunits. This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis The recombinant human GM-CSF (rh GM-CSF) stimulates the formation of macrophage, granulocyte, and eosinophil colonies in human bone marrow cell cultures. 6 It also increases erythroid and multipotential colony formation in enriched human bone marrow and peripheral blood progenitor cell cultures containing erythropoietin. 7., 8., 9., 10
M-CSF Products | Bio-Techne
Target Information. The GM-CSF gene encodes for a cytokine that regulates the production, differentiation, and function of macrophages and granulocytes. The active form of the protein exists as a homodimer in the extracellular space. This gene is located in a cluster of related genes at the chromosome region 5q31, which has been associated with G-CSF is being used clinically to facilitate hematopoietic recovery after bone marrow transplantation. Human and murine G-CSF are cross-species reactive. Recombinant Human G-CSF is an kDa protein consisting of amino acid residues. Synonyms: Granulocyte Colony-Stimulating Factor, CSF-3, MGI-1G, GM-CSF beta, pluripoietin Wounds were covered by Tegaderm dressing and treated by either PBS (control) or ml of M-CSF at a concentration of 20 ng/ml (eBioscience, Mouse M-CSF recombinant protein, 14––80) or Human M-CSF is a recombinant protein optimized for use in cell culture, differentiation studies, and functional assays. MACS GMP Recombinant Human M-CSF is designed Missing: illustrator Customers Also Purchased. Recombinant Human GM-CSF (carrier-free) - GM-CSF plays a key role in signaling emergency hemopoiesis (predominantly myelopoiesis) in response to infection, including the production of granulocytes and macrophages in the bone marrow and their maintenance, survival, and functional activation at sites of injury or insult Customized Products · Purchase Online · Quick Order · Step By Step M-CSF orientated human blood monocytes are widely used to generate monocyte-derived macrophage and model tissue macrophage. Macrophage Missing: illustrator
Construction of Recombinant Human GM-CSF and GM-CSF-ApoA …
Recombinant human M-CSF induces proliferation of M-NFS mouse myelogenous leukemia lymphoblast cells in a dose-dependent manner with an ED 50 range of - 3 Missing: illustrator Background. M-CSF, also known as CSF-1, is a four-alpha -helical-bundle cytokine that is the primary regulator of macrophage survival, proliferation and differentiation (). M-CSF is also essential for the survival and proliferation of osteoclast progenitors (1, 4). M-CSF also primes and enhances macrophage killing of tumor cells and Recombinant human M-CSF protein (Active) is a HEK Fragment protein 33 to aa range, >=95% purity 1ofPageOne RecombinantHumanM-CSF(C-6His) Catalog#:P DerivedfromHumanCells DESCRIPTION Recombinant Human Macrophage Colony-Stimulating Factor is produced by our Recombinant mouse M-CSF is a disulfide-linked homodimer containing two amino acid chains. Reconstitute using sterile water at mg/mL and centrifuge prior to opening vial. Gently pipet solution down the sides of the vial. DO NOT VORTEX sample. Store reconstituted material at ºC and add % BSA for additional stability